Antidepressants, Antipsychotics, Anxiolytics: From Chemistry by Helmut Buschmann, J?rg Holenz, Antonio Párraga, Antoni

By Helmut Buschmann, J?rg Holenz, Antonio Párraga, Antoni Torrens, José Miguel Vela, José Luis D?az

Antidepressants and comparable psychiatric medications are an important prescribed drugs world wide, accounting for a industry quantity of 20 billion US$ in line with yr. This instruction manual presents a whole and exact evaluate of all at the moment on hand psychiatric medicinal drugs, masking greater than 250 varied compounds.
specific good points include:
* an important info at the chemistry, pharmacology and healing use of a given drug
* a unique format with margin notes and compound buildings taking into consideration fast and simple entry to the specified information
Written through drug builders from the pharmaceutical undefined, novel medicines presently below improvement and new tools of remedy are indexed facet by means of facet with classical medications, permitting an immediate comparability of conventional and leading edge healing approaches.Content:
Chapter 1.1 Introductory and simple points (pages 2–50): Luz Romero, Ana Montero, Begona Fernandez and Jose M. Vela
Chapter 1.2 Clinics (pages 51–110): Rosario Perez?Egea, Victor Perez, Dolors Puigdemont and Enric Alvarez
Chapter 1.3 Pharmacology (pages 111–140): Begona Fernandez, Luz Romero and Ana Montero
Chapter 1.4 Experimental examine (pages 141–172): Ana Montero, Begona Fernandez and Luz Romero
Chapter 1.5 Chemistry (pages 173–296): Jorg Holenz, Jose Luis Diaz and Helmut Buschmann
Chapter 2.1 Introductory and uncomplicated elements (pages 298–334): Francesc Artigas
Chapter 2.2 Clinics (pages 335–388): Salvador Ros and Francisco Javier Arranz
Chapter 2.3 Pharmacology (pages 389–448): Analia Bortolozzi, Llorenc Diaz?Mataix and Francesc Artigas
Chapter 2.4 Experimental study (pages 449–489): Pau Celada, Anna Castane, Albert Adell and Francesc Artigas
Chapter 2.5 Chemistry (pages 491–616): Antonio Parraga, Jorg Holenz and Helmut Buschmann
Chapter 3.1 Introductory and easy points (pages 618–880): Francisca Lopez?Rios, Serafin Gomez?Martin and Antonio Molina?Moreno
Chapter 3.2 Clinics (pages 881–894): Blanca Gutierrez and Jorge Cervilla
Chapter 3.3 Pharmacology (pages 895–922): Jose Manuel Baeyens
Chapter 3.4 Experimental study (pages 923–949): Enrique Portillo and Jose M. Vela
Chapter 3.5 Chemistry (pages 951–1087): Monica Garca?Loapez, Susana Yenes, Helmut Buschmann and Antoni Torrens
Chapter 4.1 Introductory and uncomplicated facets (pages 1090–1103): Javier Burgueno, Rafael Franco and Francisco Ciruela
Chapter 4.2 Clinics (pages 1105–1154): Francisco Javier Arranz and Salvador Ros
Chapter 4.3 Pharmacology (pages 1155–1182): Francisco Ciruela, Rafael Franco and Javier Burgueno
Chapter 4.4 Chemistry (pages 1183–1196): Jorg Holenz, Jose Luis Diaz and Helmut Buschmann

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Additional resources for Antidepressants, Antipsychotics, Anxiolytics: From Chemistry and Pharmacology to Clinical Application

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Protease inhibitors Class of drugs designed to inhibit the enzyme protease. Protein Large, complex molecule composed of amino-acids. Proteins are essential to the structure, function, and regulation of the body. Examples are hormones, enzymes, and antibodies. Proteome Complete profile of all expressed (produced) proteins within a cell, a tissue, or an entire organism at a given time. Proteomics Analysis of the functions and interactions of proteins in healthy tissue compared to tissue affected by a disease.

Isosteres Molecules or ions of similar size containing the same number of atoms and valence electrons. Lead / Lead compound As a result of the screening process used during drug discovery, active substances will be identified. Of these active substances, the compound that best fits the desired characteristics profile (pharmacological activity, lack of early toxicity, patentability, etc) will be declared a lead compound. Development activities will then begin to shift from a broad discovery program to a more focused development program centred around the lead compound.

A. partition coefficient in 1-octanol / water) or solid-liquid (retention on reversed-phase high performance liquid chromatography (RP-HPLC) or thin-layer chromatography (TLQ System) (IUPAC). See Hydrophobicity. XXXIX Locus coeruleus A nucleus in the brain stem responsible for physiological responses to stress and panic. Macromolecule A molecule having a molecular weight in the range of a few thousand to many millions: proteins, nucleic acids and polysaccharides. Medicinal Chemistry A chemistry-based discipline, also involving aspects of biological, medical and pharmaceutical sciences.

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